A friend unfortunately told me one of his family had been diagnosed with this rare disease and that there was no detailed information whatsoever on-line. This lead me to create my first Wikipedia entry about HUV. When I was doing this I realised how vital Wikipedia is. I could have just emailed my review of some literature on the disease to my friend but by using Wiki other contributors can correct any mistakes and add more information as research continues into this intriguing autoimmune disorder.
I was recently asked about the surveillance system present within immunity which operates to kill virally infected cells by lack of MHC expression, and why this same system doesn't destroy red blood cells (RBC), which lack MHC. One function of Natural Killer (NK) cells is to destroy cells infected by viruses, which have a mechanism of evading T-cell killing by down-regulating MHC class I expression. MHC class I molecules are expressed on every cell in the body apart from RBCs; a lack of expression is detected by NK cells which act to destroy the cell. However, RBC remain unharmed. SEM of NK cells Red Blood Cells V.S Like everyone else I assumed the almighty google would provide me with the answer to my friends question, so I typed in my query and the only relevant link was to a 'yahoo answers' page, which answered a succinctly phrased question which I've used to entitle this blog entry. Unfortunately the answer just stated
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